You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet. This decreases how well Prilosec OTC works in the body.

It clears from the plasma within 4 hours, and it is completely metabolized by the liver. Metabolites are excreted mostly in the urine, and the rest via bile. Even though the half life is relatively short there is the largest effect at 24 hours, and can assist with reducing stomach acid secretion for up to 72 hours.

Prilosec OTC is a delayed-release 20mg tablet, taken once a day (every 24 hours) for 14 days before eating. You should not take it for more than 14 days or repeat a 14-day course more often than every 4 months unless directed by a doctor. Do not crush, break, or chew the tablet.

They include ranitidine (Zantac), cimetidine (Tagamet), famotidine (Pepcid) and nizatidine (Axid). In general, PPIs like omeprazole are used first because they’re better than H2 blockers at reducing stomach acid. But if a PPI does not work or causes side effects, your doctor may prescribe an H2 blocker.

Omeprazole controls acid production in the stomach only and does not affect the acid/alkaline balance of the body. The drug has been in use for some 10 years and appears to be safe for long term use. Omeprazole has not been studied when given every other day so it is not known if it is effective when given this way.

Do not take Omeprazole AN if the expiry date (EXP) printed on the bottle has passed. If you take this medicine after the expiry date has passed, it may not work as well.

An increasing number of proton pump inhibitor lawsuits are being filed against the drug makers. The lawsuits allege that the manufacturer of omeprazole and other PPIs have failed to provide important safety information regarding serious complications such as chronic kidney disease and kidney failure.

new or unusual pain in your wrist, thigh, hip, or back; seizure (convulsions); kidney problems-little or no urination, blood in your urine, swelling, rapid weight gain; low magnesium-dizziness, irregular heartbeats, feeling jittery, muscle cramps, muscle spasms, cough or choking feeling; or.

These findings indicate that omeprazole is one of the major contributors to impaired cognitive function leading to deterioration of visual and episodic memory, new learning, motor and mental response speed, short-term and sustained attention, retention and manipulation of visuospatial information, and strategy …

Some people do not need to take omeprazole every day and take it only when they have symptoms. Once you feel better (often after a few days or weeks), you can stop taking it. But taking omeprazole in this way is not suitable for everyone. Talk to your doctor about what’s best for you.